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levoketoconazole will increase the level or outcome of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.Ferraro et al (1997b) examined the in vivo dopamine and GABA levels of the nucleus accumbens in rats supplied modafinil, and they found that modafinil had an exceedingly insignificant effect on nucleus accum